【Peer-reviewed Papers & Book Chapters】
Scown, T.M., Goodhead, R.M., Johnston, B.D., Moger, J., Baalousha, M., Lead, J.R., van Aerle, R., Iguchi, T. & Tyler, C.R. (2010). Assessment of cultured fish hepatocytes for studying cellular uptake and (eco)toxicity of nanoparticles. Environmental Chemistry 7, 36–49. [Abstract]
Tyler, C.R. & Goodhead, R.M. (2010). Impact of hormone-disrupting chemicals on wildlife. In: McClean, N. (Ed.). Silent Summer - The State of Wildlife in Britain and Ireland. Cambridge University Press, pp. 125-140.
Van Aggelen, G., Ankley, G.T., Baldwin, W.S., Bearden, D.W., Benson, W.H., Chipman, j.K., Collette, T.W., Craft, J.A., Denslow, N.D., Embry, M.R., Falciani, F., George, S.G., Helbing, C.C., Hoekstra, P.F., Iguchi, T., Kagami, Y., Katsiadaki, I., Kille, P., Liu, L., Lord, P.G., McIntyre, T., O’Neill, A., Osachoff, H., Perkins, E.J., Santos, E.M., Skirrow, R.C., Snape, J.R., Tyler, C.R., Versteeg, D., Viant, M.R., Volz, D.C., Williams, T.D. & Yu, L. (2010). Integrating omic technologies into aquatic ecological risk assessment and environmental monitoring: Hurdles, achievements and future outlook. Environmental Health Perspectives 118, 1-5. [Abstract]
Goodhead, R.M. & Tyler, C.R. (2009). Endocrine-disrupting chemicals and their environmental impacts. In: Walker, C.H. (Ed.). Organic Pollutants. CRC Press, pp. 265-292.
Kumar, V., Nakada, N., Yasojima, M., Yamashita, N., Johnson, A.C. & Tanaka, H. (2009). Rapid determination of free and conjugated estrogen in different water matrices by liquid chromatography-tandem mass spectrometry. Chemosphere 77, 1440-1446. [Abstract]
Lange, A., Paull, G.C., Coe, T.S., Katsu, Y., Urushitani, H., Iguchi, T. & Tyler, C.R. (2009). Sexual reprogramming and estrogenic sensitization in wild fish exposed to ethinylestradiol. Environmental Science & Technology 43, 1219-1225. [Abstract]
Sebire, M., Scott, A.P., Tyler, C.R., Cresswell, J., Hodgson, D.J., Morris, S., Sanders, M.B., Stebbing, P.D. & Katsiadaki, I. (2009). The organophosphorous pesticide, fenitrothion, acts as an anti-androgen and alters reproductive behavior of the male three-spined stickleback, Gasterosteus aculeatus. Ecotoxicology 18, 122-133. [Abstract]
Tyler, C.R., Filby, A.L., Bickley, L.K., Cumming, R.I., Gibson, R., Labadie, P., Katsu, Y., Liney, K.E., Shears, J.A., Silva-Castro, V., Urushitani, H., Lange, A., Winter, M.J., Iguchi, T. & Hill, E.M. (2009). Environmental health impacts of equine estrogens derived from hormone replacement therapy. Environmental Science & Technology 43, 3897-3904. [Abstract]
Lange, A., Katsu, Y., Ichikawa, R., Paull, G.C., Chidgey, L.L., Coe, T.S., Iguchi, T. & Tyler, C.R. (2008). Altered sexual development in roach (Rutilus rutilus) exposed to environmental concentrations of the pharmaceutical 17a-ethinylestradiol and associated expression dynamics of aromatases and estrogen receptors. Toxicological Sciences 106, 113-123. [Abstract]
Sebire, M., Allen, Y., Bersuder, P. & Katsiadaki, I. (2008). The model anti-androgen flutamide suppresses the expression of typical male stickleback reproductive behaviour. Aquatic Toxicology 90, 37-47. [Abstract]
Sebire, M. & Katsiadaki, I. (2008). The reproductive behaviour of the three-spined stickleback as a novel assay for the detection of anti-androgens. CYBIUM, International Journal of Ichthyology 32, 59-60. [Abstract]
Iguchi, T., Katsu, Y., Urushitani, H., Lange, A. & Tyler, C.R. (2007). Developmental reproductive effects of exposure to pharmaceutical steroids in the aquatic environment: Studies on mosquitofish (Gambusia affinis affinis), roach (Rutilus rutilus) and medaka (Oryzias latipes). Journal of Marine Science and Technology-Taiwan 15 (special issue), 29-36. [Abstract]
Johnson, A., Tanaka, H., Okayasu, Y. & Suzuki, Y. (2007). Estrogen content and relative performance of Japanese and British sewage treatment plants and their potential impact on endocrine disruption. Endocrine Disrupter News Letter 10, 4-5.
Johnson, A., Tanaka, H., Okayasu, Y. & Suzuki, Y. (2007). Estrogen content and relative performance of Japanese and British sewage treatment plants and their potential impact on endocrine disruption. Environmental Sciences 14, 319-329. [Abstract]
Katsiadaki, I., Sanders, M., Sebire, M., Nagae, M., Soyano, K. & Scott, A.P. (2007). Three-spined stickleback: An emerging model in environmental endocrine disruption. Environmental Sciences 14, 263-283. [Abstract]
Katsu, Y., Lange, A., Urushitani, H., Ichikawa, R., Paull, G.C., Cahill, L.L., Jobling, S., Tyler, C.R. & Iguchi, T. (2007). Functional associations between two estrogen receptors, environmental estrogens, and sexual disruption in the roach (Rutilus rutilus). Environmental Science & Technology 41, 3368-3374. [Abstract]
Nagae, M., Kawasaki, F., Tanaka, Y., Ohkubo, N., Matsubara, T., Soyano, K., Hara, A., Arizono, K., Scott, A.P. & Katsiadaki, I. (2007). Detection and assessment of androgenic potency of endocrine-disrupting chemicals using three-spined stickleback, Gasterosteus aculeatus. Environmental Sciences 14, 255-261. [Abstract]
Pickford, D.B., Larroze, S., Takase, M., Mitsui, N., Tooi, O. & Santo, N. (2007). Investigating potential for effects of environmental endocrine disrupters on wild populations of amphibians in UK and Japan: status of historical databases and review of methods. Environmental Sciences 14, 297-317. [Abstract]
Sebire, M., Katsiadaki, I. & Scott, A.P. (2007). Non-invasive measurement of 11-ketotestosterone, cortisol and androstenedione in male three-spined stickleback (Gasterosteus aculeatus). General and Comparative Endocrinology 152, 30-38. [Abstract]
Takase, M. & Iguchi, T. (2007). Molecular cloning of two isoforms of Xenopus (Silurana) tropicalis estrogen receptor mRNA and their expression during development. Biochimica Et Biophysica Acta-Gene Structure and Expression 1769, 172-181. [Abstract]
Takase, M., Mitsui, N., Oka, T., Tooi, O., Santo, N., Pickford, D.B. & Iguchi, T. (2007). Development of biomarkers of endocrine disrupting activity in emerging amphibian model, Silurana (Xenopus) tropicalis. Environmental Sciences 14, 285-296. [Abstract]
Tyler, C.R., Filby, A.L., Iguchi, T., Kramer, V.J., Larsson, D.G.J., van Aggelen, G., van Leeuwen, K., Viant, M.R. & Tillet, D.E. (2007). Application of genomics to tiered testing. In: Ankley, G., Miracle, A., Perkins, E.J., Daston, G.P. (Eds.). Genomics in Regulatory Ecotoxicology: Applications and Challenges. CRC Press, Boca Raton.
Tyler, C.R., Lange, A., Paull, G.C., Katsu, Y. & Iguchi, T. (2007). The roach (Rutilus rutilus) as a sentinel for assessing endocrine disruption. Environmental Sciences 14, 235-253. [Abstract]
Urushitani, H., Katsu, Y., Kato, Y., Tooi, O., Santo, N., Kawashima, Y., Ohta, Y., Kisaka, Y., Lange, A., Tyler, C.R., Johnson, R.D. & Iguchi, T. (2007). Medaka (Oryzias latipes) for use in evaluating tip developmental effects of endocrine active chemicals with special reference to gonadal intersex (Testis-Ova). Environmental Sciences 14, 211-233. [Abstract]
Kawasaki, F., Katsiadaki, I., Scott, A.P., Matsubara, T., Osatomi, K., Soyano, K., Hara, A., Arizono, K. & Nagae, M. (2003). Molecular cloning of two types of spiggin cDNA in the three-spined stickleback, Gasterosteus aculeatus. Fish Physiology and Biochemistry 28, 425-425.
【Publications from Core project participants 】
Ghosh, G.C., Nakada, N., Yamashita, N. & Tanaka, H. (2010). Oseltamivir carboxylate, the active metabolite of oseltamivir phosphate (Tamiflu), detected in sewage discharge and river water in Japan. Environmental Health Perspectives 118, 103-107. [Abstract]
Halder, M., Léonard, M.A., Iguchi, T., Oris, J.T., Ryder, K., Belanger, S.E., Braunbeck, T.A., Embry, M.R., Whale, G., Norberg-King, T. & Lillicrap, A. (2010). Regulatory aspects on the use of fish embryos in environmental toxicology. Integrated Environmental Assessment and Management doi:10.1002/ieam.48. [Abstract]
Hill, E.M., Evans, K.L., Horwood, J., Rostkowski, P., Oladapo, F.O., Gibson, R., Shears, J.A. & Tyler, C.R. (2010). Profiles and some initial identifications of (anti)androgenic compounds in fish exposed to wastewater treatment works effluents. Environmental Science & Technology 44, 137-1143. [Abstract]
Johnston, B.D., Scown, T.M., Moger, J., Cumberland, S.A., Baalousha, M., Linge, K., van Aerle, R., Jarvis, K., Lead, J.R. & Tyler, C.R. (2010). Bioavailability of nanoscale metal oxides, TiO2, CeO2, and ZnO to fish. Environmental Science & Technology 44, 1144-1151. [Abstract]
Kato, Y., Kobayashi, K., Oda, S., Tatarazako, N., Watanabe, H. & Iguchi, T. (2010). Sequence divergence and expression of a transformer gene in the branchiopod crustacean Daphnia magna. Genomics doi:10.1016/j.ygeno.2009.12.005. [Abstract]
Kato, Y., Kobayashi, K., Watanabe, H. & Iguchi, T. (2010). Introduction of foreign DNA into the water flea, Daphnia magna, by electroporation. Ecotoxicology doi:10.1007/s10646-010-0460-9. [Abstract]
Katsiadaki, I., Williams, T.D., Ball, J.S., Bean, T.P., Sanders, M.B., Wu, H., Santos, E.M., Brown, M.M., Baker, P., Ortega, F., Falciani, F., Craft, J.A., Tyler, C.R., Viant, M.R. & Chipman, J.K. (2009). Hepatic transcriptomic and metabolomic responses in the stickleback (Gasterosteus aculeatus) exposed to ethinyl-estradiol. Aquatic Toxicology doi:10.1016/j.aquatox.2009.07.005. [Abstract]
Katsu, Y., Taniguchi, E., Urushitani, H., Miyagawa, S., Takase, M., Kubokawa, K., Tooi, O., Oka, T., Santo, N., Myburgh, J., Matsuno, A. & Iguchi, T. (2010). Molecular cloning and characterization of ligand- and species-specificity of amphibian estrogen receptors. General and Comparative Endocrinology doi:1016/j.ygcen.2010.01.002. [Abstract]
Moore, B.C., Milnes, M.R., Kohno, S., Katsu, Y., Iguchi, T. & Guillette, L.J.J. (2010). Influences of sex, incubation temperature, and environmental quality on gonadal estrogen and androgen receptor messenger RNA expression in juvenile American alligators (Alligator mississippiensis). Biology of Reproduction 82, 194-201. [Abstract]
Paull, G.C., Filby, A.L., Giddins, H.G., Coe, T.S., Hamilton, P.B. & Tyler, C.R. (2010). Dominance hierarchies in zebrafish (Danio rerio) and their relationship with reproductive success. Zebrafish doi:10.1089/zeb.2009.0618. [Abstract]
Santos, E.M., Ball, J.S., Williams, T.D., Wu, H., Ortega, F., van Aerle, R., Katsiadaki, I., Falciani, F., Viant, M.R., Chipman, J.K. & Tyler, C.R. (2010). Identifying health impacts of exposure to copper using transcriptomics and metabolomics in a fish model. Environmental Science & Technology 44, 820-826. [Abstract]
Bickley, L.K., Lange, A., Winter, M.J. & Tyler, C.R. (2009). Evaluation of a carp primary hepatocyte culture system for the assessment of chemicals with oestrogenic activity. Aquatic Toxicology 94, 195-203. [Abstract]
Björkblom, C., Högfors, E., Salste, L., Bergelin, E., Olsson, P.-E., Katsiadaki, I. & Wiklund, T. (2009). Estrogenic and androgenic effects of municipal wastewater effluent on reproductive endpoint biomarkers in three-spined stickleback (Gasterosteus aculeatus). Environmental Toxicology and Chemistry 28, 1063-1071. [Abstract]
Brown, A.R., Hosken, D.J., Balloux, F., Bickley, L.K., LePage, G., Owen, S.F., Hetheridge, M.J. & Tyler, C.R. (2009). Genetic variation, inbreeding and chemical exposure - combined effects in wildlife and critical considerations for ecotoxicology. Philosophical Transactions of the Royal Society B 364, 3377-3390. [Abstract]
Coe, T.S., Hamilton, P.B., Griffiths, A.M., Hodgson, D.J., Wahab, M.A. & Tyler, C.R. (2009). Genetic variation in strains of zebrafish (Danio rerio) and the implications for ecotoxicology studies. Ecotoxicology 18, 144-150. [Abstract]
Coe, T.S., Hamilton, P.B., Hodgson, D., Paull, G.C. & Tyler, C.R. (2009). Parentage outcomes in response to estrogen exposure are modified by social grouping in zebrafish. Environmental Science & Technology 43, 8400-8405. [Abstract]
Fujita, T., Scott, A., Katsiadaki, I., Amano, H., Hong, L., Hiramatsu, N., Todo, T. & Hara, A. (2009). Purification of multiple precursors for egg chorion proteins in Atlantic cod (Gadus morhua). Zoological Science. 26, 870-877. [Abstract]
Gaiser, B.K., Fernandes, T.F., Jepson, M., Lead, J.R., Tyler, C.R. & Stone, V. (2009). Assessing exposure, uptake and toxicity of silver and cerium dioxide nanoparticles from contaminated environments. Environmental Health 8 (Suppl 1), S2. [Abstract]
Grim, K.C., Wolfe, M., Braunbeck, T., Iguchi, T., Ohta, Y., Tooi, O., Touart, L., Wolf, D.C. & Tietge, J. (2009). Thyroid histopathology assessments for the amphibian metamorphosis assay to detect thyroid-active substances. Toxicologic Pathology 37, 415-424. [Abstract]
Hanamoto, S., Sugishita, H., Yamashita, N., Tanaka, H., Howa, I. & Konishi, C. (2009). Evaluation of dynamics of PPCPs at Yodo River system. Environmental Engineering Research 45, 29-37 (in Japanese). [Abstract]
Jobling, S., Burn, R.W., Thorpe, K., Williams, R. & Tyler, C. (2009). Statistical modeling suggests that antiandrogens in effluents from wastewater treatment works contribute to widespread sexual disruption in fish living in English rivers. Environmental Health Perspectives 117, 797-802. [Abstract]
Johnson, A.C., Acreman, M.C., Dunbar, M.J., Feist, S.W., Giacomello, A.M., Gozlan, R.E., Hinsley, S.A., Ibbotson, A.T., Jarvie, H.P., Jones, J.I., Longshaw, M., Maberly, S.C., Marsh, T.J., Neal, C., Newman, J.R., Nunn, M.A., Pickup, R.W., Reynard, N.S., Sullivan, C.A., Sumpter, J.P. & Williams, R.J. (2009). The British river of the future: How climate change and human activity might affect two contrasting river ecosystems in England. Science of the Total Environment 407, 4787-4798. [Abstract]
Jolly, C., Katsiadaki, I., Morris, S., Le Belle, N., Dufour, S., Mayer, I., Pottinger, T.G. & Scott, A.P. (2009). Detection of the anti-androgenic effect of endocrine disrupting environmental contaminants using in vivo and in vitro assays in the three-spined stickleback. Aquatic Toxicology 92, 228-239. [Abstract]
Jürgens, M.D., Johnson, A.C., Pottinger, T.G. & Sumpter, J.P. (2009). Do suspended sediments modulate the effects of octylphenol on rainbow trout? Water Research 43, 1381-1391. [Abstract]
Kim, H., Hayashi, S., Chambon, P., Watanabe, H., Iguchi, T. & Sato, T. (2009). Effects of diethylstilbestrol on ovarian follicle development in neonatal mice. Reproductive Toxicology 27, 55-62. [Abstract]
Kim, H., Nakajima, T., Hayashi, S., Chambon, P., Watanabe, H., Iguchi, T. & Sato, T. (2009). Effects of diethylstilbestrol on programmed oocyte death and induction of polyovular follicles in neonatal mouse ovaries. Biology of Reproduction 81, 1002-1009. [Abstract]
Kim, I. & Tanaka, H. (2009). Photodegradation characteristics of PPCPs in water with UV treatment. Environment International 35, 793-802. [Abstract]
Kim, I., Yamashita, N. & Tanaka, H. (2009). Performance of UV and UV/H2O2 processes for the removal of pharmaceuticals detected in secondary effluent of a sewage treatment plant in Japan. Journal of Hazardous Materials 166, 1134-1140. [Abstract]
Kim, I., Yamashita, N. & Tanaka, H. (2009). Photodegradation of pharmaceuticals and personal care products during UV and UV/H2O2 treatments. Chemosphere 77, 518-525. [Abstract]
Kim, I.H., Yamashita, N., Kato, Y. & Tanaka, H. (2009). Discussion on the application of UV/H2O2, O-3 and O-3/UV processes as technologies for sewage reuse considering the removal of pharmaceuticals and personal care products. Water Science and Technology 59, 945-955. [Abstract]
Kirigaya, A., Kim, H., Hayashi, S., Chambon, P., Watanabe, H., Iguchi, T. & Sato, T. (2009). Involvement of estrogen receptor b in the induction of polyovular follicles in mouse ovaries exposed neonatally to diethylstilbestrol. Zoological Science 26, 704-712. [Abstract]
Macnab, V., Katsiadaki, I. & Barber, I. (2009). Reproductive potential of Schistocephalus solidus -infected male three-spined stickleback (Gasterosteus aculeatus) from two UK populations. . Journal of Fish Biology 75, 2095-2107. [Abstract]
Miyagawa, S., Katsu, Y., Ohta, Y., Sudo, T., Lubahn, D.B. & Iguchi, T. (2009). Estrogen receptor ESR1 is indispensable for the induction of persistent vaginal change by neonatal 5a-dihydrotestosterone exposure. Biology of Reproduction doi: 10.1095/biolreprod.109.081315. [Abstract]
Miyagawa, S., Moon, A., Haraguchi, R., Inoue, C., Harada, M., Nakahara, C., Suzuki, K., Matsumaru, D., Kaneko, T., Matsuo, I., Yang, L., Taketo, M.M., Iguchi, T., Evans, S.M. & Yamada, G. (2009). Dosage-dependent hedgehog signals integrated with Wnt/b-catenin signaling regulate embryonic external genitalia formation as an appendicular program. Development 136, 3969-3978. [Abstract]
Miyagawa, S., Satoh, Y., Haraguchi, R., Suzuki, K., Iguchi, T., Taketo, M.M., Nakagata, N., Matsumoto, T., Takeyama, K., Kato, S. & Yamada, G. (2009). Genetic interactions of the androgen and Wnt/b-catenin pathways for the masculinization of external genitalia. Molecular Endocrinology 23, 871-880. [Abstract]
Myers, J.P., vom Saal, F.S., Akingbemi, B.T., Arizono, K., Belcher, S., Colborn, T., Chahoud, I., Crain, D.A., Farabollini, F., Guillette, L.J., Hassold, T., Ho, S.M., Hunt, P.A., Iguchi, T., Jobling, S., Kanno, J., Laufer, H., Marcus, M., McLachlan, J.A., Nadal, A., Oehlmann, J., Olea, N., Palanza, P., Parmigiani, S., Rubin, B.S., Schoenfelder, G., Sonnenschein, C., Soto, A.M., Taisness, C.E., Taylor, J.A., Vandenberg, L.N., Vandenbergh, J.G., Vogel, S., Watson, C.S., Welshons, W.V. & Zoeller, R.T. (2009). Why public health agencies cannot depend on good laboratory practices as a criterion for selecting data: The case of bisphenol A. Environmental Health Perspectives 117, 309-315. [Abstract]
Oehlmann, J., Schulte-Oehlmann, U., Kloas, W., Jagnytsch, O., Lutz, I., Kusk, K.O., Wollenberger, L., Santos, E.M., Paull, G.C., Van Look, K.J.W. & Tyler, C.R. (2009). A critical analysis of the biological impacts of plasticizers on wildlife. Philosophical Transactions of the Royal Society B-Biological Sciences 364, 2047-2062. [Abstract]
Oka, T., Miyahara, M., Yamamoto, J., Mitsui, N., Fujii, T., Tooi, O., Kashiwagi, K., Takase, M., Kashiwagi, A. & Iguchi, T. (2009). Application of metamorphosis assay to a native Japanese amphibian species, Rana rugosa, for assessing effects of thyroid system affecting chemicals. Ecotoxicology and Environmental Safety 72, 1400-1405. [Abstract]
Paull, G.C., Filby, A.L. & Tyler, C.R. (2009). Growth rate during early life affects sexual differentiation in roach (Rutilus rutilus). Environmental Biology of Fishes 85, 277-284. [Abstract]
Scown, T.M., van Aerle, R., Johnston, B.D., Cumberland, S., Lead, J.R., Owen, R. & Tyler, C.R. (2009). High doses of intravenously administered titanium dioxide nanoparticles accumulate in the kidneys of rainbow trout but with no observable impairment of renal function. Toxicological Sciences 109, 372-380. [Abstract]
Sebire, M., Katsiadaki, I. & Scott, A.P. (2009). Further refinement of the non-invasive procedure for measuring steroid production in the male stickleback, Gasterosteus aculeatus L. Journal of Fish Biology 75, 2082-2094. [Abstract]
Thorpe, K.L., Maack, G., Benstead, R. & Tyler, C.R. (2009). Estrogenic wastewater treatment works effluents reduce egg production in fish. Environmental Science & Technology 43, 2976-2982. [Abstract]
Williams, R.J., Keller, V.D.J., Johnson, A.C., Young, A.R., Holmes, M.G.R., Wells, C., Gross-Sorokin, M. & Benstead, R. (2009). A national risk assessment for intersex in fish arising from steroid estrogens. Environmental Toxicology and Chemistry 28, 220-230. [Abstract]
Williams, T.D., Wu, H.F., Santos, E.M., Ball, J., Katsiadaki, I., Brown, M.M., Baker, P., Ortega, F., Falciani, F., Craft, J.A., Tyler, C.R., Chipman, J.K. & Viant, M.R. (2009). Hepatic transcriptomic and metabolomic responses in the stickleback (Gasterosteus aculeatus) exposed to environmentally relevant concentrations of dibenzanthracene. Environmental Science & Technology 43, 6341-6348. [Abstract]
Allen, Y.T., Katsiadaki, I., Pottinger, T.G., Jolly, C., Matthiessen, P., Mayer, I., Smith, A., Scott, A.P., Eccles, P., Sanders, M.B., Pulman, K.G.T. & Feist, S. (2008). Intercalibration exercise using a stickleback endocrine disrupter screening assay. Environmental Toxicology and Chemistry 27, 404-412. [Abstract]
Aniagu, S.O., Williams, T.D., Allen, Y., Katsiadaki, I. & Chipman, J.K. (2008). Global genomic methylation levels in the liver and gonads of the three-spine stickleback (Gasterosteus aculeatus) after exposure to hexabromocyclododecane and 17-b oestradiol. Environment International 34, 310-317. [Abstract]
Björkblom, C., Salste, L., Katsiadaki, I., Wiklund, T. & Kronberg, L. (2008). Detection of estrogenic activity in municipal wastewater effluent using primary cell cultures from three-spined stickleback and chemical analysis. Chemosphere 73, 1064-1070. [Abstract]
Brown, M.M., Williams, T.D., Chipman, J.K., Katsiadaki, I., Sanders, M. & Craft, J.A. (2008). Construction of subtracted EST and normalised cDNA libraries from liver of chemical-exposed three-spined stickleback (Gasterosteus aculeatus) containing pollutant-responsive genes as a resource for transcriptome analysis. Marine Environmental Research 66, 127-130. [Abstract]
Coe, T.S., Hamilton, P.B., Hodgson, D., Paull, G.C., Stevens, J.R., Sumner, K. & Tyler, C.R. (2008). An environmental estrogen alters reproductive hierarchies, disrupting sexual selection in group-spawning fish. Environmental Science & Technology 42, 5020-5025. [Abstract]
Crain, D.A., Janssen, S.J., Edwards, T.M., Heindel, J., Ho, S.M., Hunt, P., Iguchi, T., Juul, A., McLachlan, J.A., Schwartz, J., Skakkebaek, N., Soto, A.M., Swan, S., Walker, C., Woodruff, T.K., Woodruff, T.J., Giudice, L.C. & Guillette, L.J. (2008). Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing. Fertility and Sterility 90, 911-940. [Abstract]
Filby, A.L., van Aerle, R., Duitman, J. & Tyler, C.R. (2008). The kisspeptin/gonadotropin-releasing hormone pathway and molecular signaling of puberty in fish. Biology of Reproduction 78, 278-289. [Abstract]
Geoghegan, F., Katsiadaki, I., Williams, T.D. & Chipman, J.K. (2008). A cDNA microarray for the three-spined stickleback, Gasterosteus aculeatus L., and analysis of the interactive effects of oestradiol and dibenzanthracene exposures. Journal of Fish Biology 72, 2133-2153. [Abstract]
Hamilton, P.B. & Tyler, C.R. (2008). Identification of microsatellite loci for parentage analysis in roach Rutilus rutilus and eight other cyprinid fish by cross-species amplification, and a novel test for detecting hybrids between roach and other cyprinids. Molecular Ecology Resources 8, 462-465. [Abstract]
Handy, R.D., Henry, T.B., Scown, T.M., Johnston, B.D. & Tyler, C.R. (2008). Manufactured nanoparticles: their uptake and effects on fish-a mechanistic analysis. Ecotoxicology 17, 396-409. [Abstract]
Iguchi, T. & Katsu, Y. (2008). Commonality in signaling of endocrine disruption from snail to human. Bioscience 58, 1061-1067. [Abstract]
Iguchi, T., Watanabe, H. & Katsu, Y. (2008). Toxicogenomics and ecotoxicogenomics: Studying chemical effects and basic biology in vertebrates and invertebrates. In: Sahu, S. (Ed.). Toxicogenomics: A Powerful Tool for Toxicology Assessment. John Wiley & Sons, pp. 143-158.
Iguchi, T., Watanabe, H., Ohta, Y. & Blumberg, B. (2008). Developmental effects: oestrogen-induced vaginal changes and organotin-induced adipogenesis. International Journal of Andrology 31, 263-268. [Abstract]
Johnson, A.C., Ternes, T., Williams, R.J. & Sumpter, J.P. (2008). Assessing the concentrations of polar organic microcontaminants from point sources in the aquatic environment: Measure or model? Environmental Science & Technology 42, 5390-5399. [Abstract]
Katsu, Y., Ichikawa, R., Ikeuchi, T., Kohno, S., Guillette, L.J. & Iguchi, T. (2008). Molecular cloning and characterization of estrogen, androgen, and progesterone nuclear receptors from a freshwater turtle (Pseudemys nelsoni). Endocrinology 149, 161-173. [Abstract]
Katsu, Y., Kohno, S., Hyodo, S., Ijiri, S., Adachi, S., Hara, A., Guillette, L.J. & Iguchi, T. (2008). Molecular cloning, characterization, and evolutionary analysis of estrogen receptors from phylogenetically ancient fish. Endocrinology 149, 6300-6310. [Abstract]
Kohno, S., Katsu, Y., Iguchi, T. & Guillette, L.J. (2008). Novel approaches for the study of vertebrate steroid hormone receptors. Integrative and Comparative Biology 48, 527-534. [Abstract]
Moger, J., Johnston, B.D. & Tyler, C.R. (2008). Imaging metal oxide nanoparticles in biological structures with CARS microscopy. Optics Express 16, 3408-3419. [Abstract]
Naidoo, V., Katsu, Y. & Iguchi, T. (2008). The influence of non-toxic concentrations of DDT and DDE on the old world vulture estrogen receptor alpha. General and Comparative Endocrinology 159, 188-195. [Abstract]
Nakamura, T., Katsu, Y., Watanabe, H. & Iguchi, T. (2008). Estrogen receptor subtypes selectively mediate female mouse reproductive abnormalities induced by neonatal exposure to estrogenic chemicals. Toxicology 253, 117-124. [Abstract]
Oka, T., Tooi, O., Mitsui, N., Miyahara, M., Ohnishi, Y., Takase, M., Kashiwagi, A., Shinkai, T., Santo, N. & Iguchi, T. (2008). Effect of atrazine on metamorphosis and sexual differentiation in Xenopus laevis. Aquatic Toxicology 87, 215-226. [Abstract]
Paull, G.C., Lange, A., Henshaw, A.C. & Tyler, C.R. (2008). Ontogeny of sexual development in the roach (Rutilus rutilus) and its interrelationships with growth and age. Journal of Morphology 269, 884-895. [Abstract]
Paull, G.C., Van Look, K.J.W., Santos, E.M., Filby, A.L., Gray, D.M., Nash, J.P. & Tyler, C.R. (2008). Variability in measures of reproductive success in laboratory-kept colonies of zebrafish and implications for studies addressing population-level effects of environmental chemicals. Aquatic Toxicology 87, 115-126. [Abstract]
Sanchez, W., Katsiadaki, I., Piccini, B., Ditche, J.M. & Porcher, J.M. (2008). Biomarker responses in wild three-spined stickleback (Gasterosteus aculeatus L.) as a useful tool for freshwater biomonitoring: A multiparametric approach. Environment International 34, 490-498. [Abstract]
Sanders, M.B., Sebire, M., Sturve, J., Christian, P., Katsiadaki, I., Lyons, B.P., Sheahan, D., Weeks, J.M. & Feist, S.W. (2008). Exposure of sticklebacks (Gasterosteus aculeatus) to cadmium sulfide nanoparticles: Biological effects and the importance of experimental design. Marine Environmental Research 66, 161-163. [Abstract]
Santos, E.M., Kille, P., Workman, V.L., Paull, G.C. & Tyler, C.R. (2008). Sexually dimorphic gene expression in the brains of mature zebrafish. Comparative Biochemistry and Physiology A 149, 314-324. [Abstract]
Sumpter, J.P. & Johnson, A.C. (2008). 10th Anniversary Perspective: Reflections on endocrine disruption in the aquatic environment: from known knowns to unknown unknowns (and many things in between). Journal of Environmental Monitoring 10, 1476-1485. [Abstract]
Takao, Y., Oishi, M., Nagae, M., Kohra, S. & Arizono, K. (2008). Bisphenol A incorporated into eggs from parent fish persists for several days. Journal of Health Science 54, 235-239. [Abstract]
Takao, Y., Shimazu, M., Fukuda, M., Ishibashi, H., Nagae, M., Kohra, S., Tabira, Y., Ishibashi, Y. & Arizono, K. (2008). Seasonal and diurnal fluctuations in the concentrations of pharmaceuticals and personal care products (PPCPs) in residential sewage water. Journal of Health Science 54, 240-243. [Abstract]
Thorpe, K.L., Benstead, R., Eccles, P., Maack, G., Williams, T. & Tyler, C.R. (2008). A practicable laboratory flow-through exposure system for assessing the health effects of effluents in fish. Aquatic Toxicology 88, 164-172. [Abstract]
Tyler, C.R., Filby, A.L., van Aerle, R., Lange, A., Ball, S. & Santos, E.M. (2008). Fish toxicogenomics. In: Hogstrand, C., Kille, P. (Eds.). Comparative Toxicogenomics. Elsevier, Amsterdam, The Netherlands, pp. 75-132, 324-325. [Abstract]
Tyler, C.R. & Jobling, S. (2008). Roach, sex, and gender-bending chemicals: The feminization of wild fish in English rivers. Bioscience 58, 1051-1059. [Abstract]
van Aerle, R., Kille, P., Lange, A. & Tyler, C.R. (2008). Evidence for the existence of a functional Kiss1/Kiss1 receptor pathway in fish. Peptides 29, 57-64. [Abstract]
Watanabe, H., Kobayashi, K., Kato, Y., Oda, S., Abe, R., Tatarazako, N. & Iguchi, T. (2008). Genomic response in Daphnia to chemical pollutants. In: Murakami, Y., Nakayama, K., Kitamura, S.-I., Iwata, H., Tanabe, S. (Eds.). Interdisciplinary Studies on Environmental Chemistry – Biological Responses to Chemical Pollutants. TERRAPUB, pp. 133-142.
Watanabe, H., Kobayashi, K., Kato, Y., Oda, S., Abe, R., Tatarazako, N. & Iguchi, T. (2008). Transcriptome profiling in crustaceans as a tool for ecotoxicogenomics. Cell Biology and Toxicology 24, 641-647. [Abstract]
Amano, H., Fujita, T., Hiramatsu, N., Shimizu, M., Sawaguch, S., Iatsubara, T., Kagawa, H., Nagae, M., Sullivan, C.V. & Hara, A. (2007). Egg yolk proteins in gray mullet (Mugil cephalus): Purification and classification of multiple lipovitellins and other vitellogenin-derived yolk proteins and molecular cloning of the parent vitellogenin genes. Journal of Experimental Zoology Part A-Ecological Genetics and Physiology 307A, 324-341. [Abstract]
Andersson, C., Katsiadaki, I., Lundstedt-Enkel, K. & Orberg, J. (2007). Effects of 17a-ethynylestradiol on EROD activity, spiggin and vitellogenin in three-spined stickleback (Gasterosteus aculeatus). Aquatic Toxicology 83, 33-42. [Abstract]
Björkblom, C., Olsson, P.-E., Katsiadaki, I. & Wiklund, T. (2007). Estrogen- and androgen-sensitive bioassays based on primary cell and tissue slice cultures from three-spined stickleback (Gasterosteus aculeatus). Comparative Biochemistry and Physiology C 146, 431-442. . [Abstract]
Filby, A.L., Neuparth, T., Thorpe, K.L., Owen, R., Galloway, T.S. & Tyler, C.R. (2007). Health impacts of estrogens in the environment, considering complex mixture effects. Environmental Health Perspectives 115, 1704-1710. [Abstract]
Filby, A.L., Santos, E.M., Thorpe, K.L., Maack, G. & Tyler, C.R. (2007). Gene expression profiling for understanding chemical causation of biological effects for complex mixtures: A case study on Estrogens. Environmental Science & Technology 41, 8187-8194. [Abstract]
Filby, A.L., Thorpe, K.L., Maack, G. & Tyler, C.R. (2007). Gene expression profiles revealing the mechanisms of anti-androgen-and estrogen-induced feminization in fish. Aquatic Toxicology 81, 219-231. [Abstract]
Filby, A.L. & Tyler, C.R. (2007). Appropriate 'housekeeping' genes for use in expression profiling the effects of environmental estrogens in fish. BMC Molecular Biology 8. [Abstract]
Guillette, L.J., Jr., Edwards, T.M. & Moore, B.C. (2007). Alligators, contaminants and steroid hormones. Environmental Sciences 14, 331-347. [Abstract]
Iguchi, T., Watanabe, H. & Katsu, Y. (2007). Toxicogenomics and ecotoxicogenomics for studying endocrine disruption and basic biology. General and Comparative Endocrinology 153, 25-29. [Abstract]
Johnson, A.C., Williams, R.J., Simpson, P. & Kanda, R. (2007). What difference might sewage treatment performance make to endocrine disruption in rivers? Environmental Pollution 147, 194-202. [Abstract]
Katsu, Y., Hinago, M., Sone, K., Urushitani, H., Guillette, L.J. & Iguchi, T. (2007). In vitro assessment of transcriptional activation of the estrogen and androgen receptors of mosquitofish, Gambusia affinis affinis. Molecular and Cellular Endocrinology 276, 10-17. [Abstract]
Pettersson, M., Hahlbeck, E., Katsiadaki, L., Asplund, L. & Bengtsson, B.E. (2007). Survey of estrogenic and androgenic disruption in Swedish coastal waters by the analysis of bile fluid from perch and biomarkers in the three-spined stickleback. Marine Pollution Bulletin 54, 1868-1880. [Abstract]
Rushbrook, B.J., Katsiadaki, I. & Barber, I. (2007). Spiggin levels are reduced in male sticklebacks infected with Schistocephalus solidus. Journal of Fish Biology 71, 298-303. [Abstract]
Santos, E.M., Paull, G.C., Van Look, K.J.W., Workman, V.L., Holt, W.V., van Aerle, R., Kille, P. & Tyler, C.R. (2007). Gonadal transcriptome responses and physiological consequences of exposure to oestrogen in breeding zebrafish (Danio rerio). Aquatic Toxicology 83, 134-142. [Abstract]
Santos, E.M., Workman, V.L., Paull, G.C., Filby, A.L., Van Look, K.J.W., Kille, P. & Tyler, C.R. (2007). Molecular basis of sex and reproductive status in breeding zebrafish. Physiological Genomics 30, 111-122. [Abstract]
Schulz, R.W., Bogerd, J., Male, R., Ball, J., Fenske, M., Olsen, L.C. & Tyler, C.R. (2007). Estrogen-induced alterations in amh and dmrt1 expression signal for disruption in male sexual development in the zebrafish. Environmental Science & Technology 41, 6305-6310. [Abstract]
Thorpe, K.L., Benstead, R., Hutchinson, T.H. & Tyler, C.R. (2007). Associations between altered vitellogenin concentrations and adverse health effects in fathead minnow (Pimephales promelas). Aquatic Toxicology 85, 176-183. [Abstract]
Hirobe, M., Goda, Y., Okayasu, Y., Tomita, J., Takigami, H., Ike, M. & Tanaka, H. (2006). The use of enzyme-linked immunosorbent assays (ELISA) for the determination of pollutants in environmental and industrial wastes. Water Science and Technology 54, 1-9. [Abstract]
Iguchi, T., Irie, F., Urushitani, H., Tooi, O., Kawashima, Y., Roberts, M., Norrgren, L. & Hutchinson, T.H. (2006). Availability of in vitro vitellogenin assay for screening of estrogenic and anti-estrogenic activities of environmental chemicals. Environmental Sciences 13, 161-183. [Abstract]
Iguchi, T., Watanabe, H. & Katsu, Y. (2006). Application of ecotoxicogenomics for studying endocrine disruption in vertebrates and invertebrates. Environmental Health Perspectives 114, 101-105. [Abstract]
Jolly, C., Katsiadaki, I., Le Belle, N., Mayer, I. & Dufour, S. (2006). Development of a stickleback kidney cell culture assay for the screening of androgenic and anti-androgenic endocrine disrupters. Aquatic Toxicology 79, 158-166. [Abstract]
Katsiadaki, I., Morris, S., Squires, C., Hurst, M.R., James, J.D. & Scott, A.P. (2006). Use of the three-spined stickleback (Gasterosteus aculeatus) as a sensitive in vivo test for detection of environmental antiandrogens. Environmental Health Perspectives 114, 115-121. [Abstract]
Katsiadaki, I. & Scott, A.P. (2006). The stickleback model in endocrine disruption research: An essential tool in the laboratory and the field. Marine Environmental Research 62, S228-S229. [Abstract]
Katsu, Y., Kohno, S., Oka, T., Mitsui, N., Tooi, O., Santo, N., Urushitani, H., Fukumoto, Y., Kuwabara, K., Ashikaga, K., Minami, S., Kato, S., Ohta, Y., Guillette, L.J. & Iguchi, T. (2006). Molecular cloning of estrogen receptor alpha (ERa; ESR1) of the Japanese giant salamander, Andrias japonicus. Molecular and Cellular Endocrinology 257-258, 84-94. [Abstract]
Komori, K., Okayasu, Y., Yasojima, M., Suzuki, Y. & Tanaka, H. (2006). Occurrence of nonylphenol, nonylphenol ethoxylate surfactants and nonylphenol carboxylic acids in wastewater in Japan. Water Science and Technology 53, 27-33. [Abstract]
Mitsui, N., Fujii, T., Miyahara, M., Oka, T., Kashiwagi, A., Kashiwagi, K., Hanada, H., Urushitani, H., Santo, N., Tooi, O. & Iguchi, T. (2006). Development of metamorphosis assay using Silurana tropicalis for the detection of thyroid system-disrupting chemicals. Ecotoxicology and Environmental Safety 64, 281-287. [Abstract]
Nakada, N., Yasojima, M., Okayasu, Y., Komori, K., Tanaka, H. & Suzuki, Y. (2006). Fate of oestrogenic compounds and identification of oestrogenicity in a wastewater treatment process. Water Science and Technology 53, 51-63. [Abstract]
Oka, T., Mitsui, N., Hinago, M., Miyahara, M., Fujii, T., Tooi, O., Santo, N., Urushitani, H., Iguchi, T., Hanaoka, Y. & Mikami, H. (2006). All ZZ male Xenopus laevis provides a clear sex-reversal test for feminizing endocrine disruptors. Ecotoxicology and Environmental Safety 63, 236-243. [Abstract]
Yamashita, N., Tanaka, H., Miyajima, K., Tamamoto, H., Miyamoto, N., Yasojima, M., Komori, K. & Suzuki, Y. (2006). Fate estimation of estrogenic substances in an urban river by flux calculation. Water Environment Research 78, 2330-2334. [Abstract]
Higashitani, T., Miyajima, K., Nakada, N., Yasojima, M., Tanaka, H. & Suzuki, Y. (2005). Development of on-site fish exposure system placed in water quality monitoring stations along a river. Water Science and Technology 52, 275-282. [Abstract]
Nagae, M., Shiroyama, K., Inoue, M., Hara, A., Takao, Y., Kohra, S., Ishibashi, Y., Tominaga, N., Yoshihara, S. & Arizono, K. (2005). Estrogenic potency of a bisphenol A metabolite on vitellogenin synthesis in medaka, Oryzias latipes. Journal of Health Science 51, 93-95. [Abstract]
Komori, K., Tanaka, H., Okayasu, Y., Yasojima, M. & Sato, C. (2004). Analysis and occurrence of estrogen in wastewater in Japan. Water Science and Technology 50, 93-100. [Abstract]
Mibu, K., Wada, J., Okayasu, Y., Tsumori, J., Komori, K., Tanaka, H., Li, J.H., Sasaki, M. & Sato, C. (2004). Distribution of estrogen, nonylphenol and its derivatives in the sediments of a shallow lake. Water Science and Technology 50, 173-179. [Abstract]
Higashitani, T., Tamamoto, H., Takahashi, A. & Tanaka, H. (2003). Study of estrogenic effects on carp (Cyprinus carpio) exposed to sewage treatment plant effluents. Water Science and Technology 47, 93-100. [Abstract]
Takahashi, A., Higashitani, T., Yakou, Y., Saitou, M., Tamamoto, H. & Tanaka, H. (2003). Evaluating bioaccumulation of suspected endocrine disruptors into periphytons and benthos in the Tama River. Water Science and Technology 47, 71-76. [Abstract]