Peer-reviewed Papers
【Core 1 】
Andrew Johnson, Hiroaki Tanaka, Yuji Okayasu and Yutaka Suzuki: The estrogen content and relative performance of Japanese and British sewage treatment plants and their potential impact on endocrine disruption. Environ Sci. 2007;14(6):319-29. PMID:18030286
Johnson A, Tanaka H, Okayasu Y, Suzuki Y: Estrogen content and relative performance of Japanese and British sewage treatment plants and their potential impact on endocrine disruption. Endocrine Disrupter News Letter 2007, 10:4-5.
Hirobe M, Goda Y, Okayasu Y, Tomita J, Takigami H, Ike M, Tanaka H: The use of enzyme-linked immunosorbent assays (ELISA) for the determination of pollutants in environmental and industrial wastes. Water Science and Technology 2006, 54(11-12):1-9.
Komori K, Okayasu Y, Yasojima M, Suzuki Y, Tanaka H: Occurrence of nonylphenol, nonylphenol ethoxylate surfactants and nonylphenol carboxylic acids in wastewater in Japan. Water Science and Technology 2006, 53(11):27-33.
Nakada N, Yasojima M, Okayasu Y, Komori K, Tanaka H, Suzuki Y: Fate of oestrogenic compounds and identification of oestrogenicity in a wastewater treatment process. Water Science and Technology 2006, 53(11):51-63.
Yamashita N, Tanaka H, Miyajima K, Tamamoto H, Miyamoto N, Yasojima M, Komori K, Suzuki Y: Fate estimation of estrogenic substances in an urban river by flux calculation. Water Environment Research 2006, 78(12):2330-2334.
Higashitani T, Miyajima K, Nakada N, Yasojima M, Tanaka H, Suzuki Y: Development of on-site fish exposure system placed in water quality monitoring stations along a river. Water Science and Technology 2005, 52(12):275-282.
Li FS, Yuasa A, Obara A, Mathews AP: Aerobic batch degradation of 17-beta estradiol (E2) by activated sludge: Effects of spiking E2 concentrations, MLVSS, and temperatures. Water Research 2005, 39(10):2065-2075.
【Core 2】
Allen YT, Katsiadaki I, Pottinger TG, Jolly C, Matthiessen P, Mayer I, Smith A, Scott AP, Eccles P, Sanders MB, Pulman KGT, Feist S: Intercalibration exercise using a stickleback endocrine disrupter screening assay. Environmental Toxicology and Chemistry 2008, 27(2):404-412.
Sebire M, Allen Y, Bersuder P, Katsiadaki I: The model anti-androgen flutamide suppresses the expression of typical male stickleback reproductive behaviour. Aquatic Toxicology 2008, doi:10.1016/j.aquatox.2008.07.016.
Sebire M, Katsiadaki I: The reproductive behaviour of the three-spined stickleback as a novel assay for the detection of anti-androgens. CYBIUM, International Journal of Ichthyology 2008, 32(2 suppl):59-60.
Sebire M, Scott AP, Tyler CR, Cresswell J, Hodgson DJ, Morris S, Sanders MB, Stebbing PD, Katsiadaki I: The organophosphorous pesticide, fenitrothion, acts as an anti-androgen and alters reproductive behavior of the male three-spined stickleback, Gasterosteus aculeatus. Ecotoxicology 2009, 18 (1): 122-133
Masaki Nagae, Fumie Kawasaki, Yuka Tanaka, Nobuyuki Ohkubo, Takahiro Matsubara, Kiyoshi Soyano, Akihiko Hara, Koji Arizono, Alexander P. Scott and Ioanna Katsiadaki: Detection and assessment of androgenic potency of endocrine-disrupting chemicals using the three-spined stickleback, Gasterosteus aculeatus. Environ. Sci. 2007;14(5):255-61. PMID:17975537
Ioanna Katsiadaki, Matthew Sanders, Marion Sebire, Masaki Nagae, Kiyoshi Soyano and Alexander Pickering Scott: The three-spined stickleback: an emerging model in environmental endocrine disruption. Environ. Sci. 2007;14(5):263-83. PMID: 17975538
Sebire M, Katsiadaki I, Scott AP: Non-invasive measurement of 11-ketotestosterone, cortisol and androstenedione in male three-spined stickleback (Gasterosteus aculeatus). General and Comparative Endocrinology 2007, 152(1):30-38.
Katsiadaki I, Scott AP: The stickleback model in endocrine disruption research: An essential tool in the laboratory and the field. Marine Environmental Research 2006, 62:S228-S229.
Kawasaki, F., Katsiadaki, I, Scott, A.P., Matsubara, T., Osatomi, K., Soyano, K., Hara, A., Arizono, K., and Nagae, M. 2003. Molecular cloning of two types of spiggin cDNA in the three-spined stickleback, Gasterosteus aculeatus. Fish Physiology and Biochemistry 28: 425
【Core 3】
Charles R. Tyler, Amy L. Filby, Lisa K. Bickley, Rob I. Cumming, Richard Gibson, Pierre Labadie, Yoshinao Katsu, Katherine E. Liney, Janice A. Shears, Vanessa Silva-Castro, Hiroshi Urushitani, Anke Lange, Matthew J. Winter, Taisen Iguchi, and Elizabeth M. Hill 2009: Environmental Health Impacts of Equine Estrogens Derived from Hormone Replacement Therapy. Environmental Science & Technology 2009, 43 (10), 3897-3904
Anke Lange, Gregory C. Paull, Tobias S. Coe, Yoshinao Katsu, Hiroshi Urushitani, Taisen Iguchi, and Charles R. Tyler Sexual Reprogramming and Estrogenic Sensitization in Wild Fish Exposed to Ethinylestradiol. Environmental Science & Technology 2009, 43 (4), 1219-1225 supplementary material
Anke Lange, Yoshinao Katsu, Rie Ichikawa, Gregory C. Paull, Laura L. Chidgey, Tobias S. Coe, Taisen Iguchi, and Charles R. Tyler Altered Sexual Development in Roach (Rutilus rutilus) Exposed to Environmental Concentrations of the Pharmaceutical 17a-Ethinylestradiol and Associated Expression Dynamics of Aromatases and Estrogen Receptors Toxicological Sciences 106(1), 113–123 (2008) - supplementary material PMID: 18653663
Tyler CR, Filby AL, Iguchi T, Kramer VJ, Larsson DGJ, van Aggelen G, van Leeuwen K, Viant MR, Tillet DE: Application of genomics to tiered testing. In: Genomics in Regulatory Ecotoxicology: Applications and Challenges. Edited by Ankley G, Miracle A, Perkins EJ, Daston GP. Boca Raton: CRC Press; 2007.
Taisen Iguchi, Yoshinao Katsu, Hiroshi Urushitani, Anke Lange and Charles R. Tyler: Developmental reproductive effects of exposure to pharmaceutical steroids in the aquatic environment: studies on mosquitofish (Gambusia affinis affinis), roach (Rutilus rutilus) and medaka (Oryzias latipes). Journal of Marine Science and Technology 15 (special issue): 29-36, 2007.
Katsu, Y., A. Lange, R. Ichikawa, H. Urushitani, G.C. Paull, L.L. Cahill, S. Jobling, C.R. Tyler and T. Iguchi: Functional associations between two estrogen receptors, environmental estrogen and sexual disruption in the roach (Rutilus rutilus). Environmental Science & Technology,41: 3360-3374, 2007. Supporting information
Hiroshi Urushitani, Yoshinao Katsu, Yasuhiko Kato, Osamu Tooi, Noriaki Santo, Yukio Kawamura, Yasuhiko Ohta, Yumi Kisaka, Anke Lange, Charles R. Tyler, Rodney D. Johnson and Taisen Iguchi : The Medaka (Oryzias latipes) for use in evaluating developmental effects of endocrine active chemicals with special reference to gonadal intersex (testis-ova). Environ. Sci. 2007;14(5):211-33. PMID: 17975535
Charles R. Tyler, Anke Lange, Gregory C. Paull, Yoshinao Katsu and Taisen Iguchi: The roach (Rutilus rutilus) as a sentinel for assessing endocrine disruption. Environ. Sci. 2007;14(5):235-53. PMID: 17975536
【Core 4】
Minoru Takase and Taisen Iguchi: Molecular cloning of two isoforms of Xenopus (Silurana tropicalis) estrogen receptor mRNA and their expression during development. Biophys. Biochem. Acta, 1769: 172-181, 2007.
Minoru Takase, Naoko Mitsui, Tomohiro Oka, Osamu Tooi, Noriaki Santo, Daniel Pickford and Taisen Iguchi : Development of biomarkers for endocrine disrupting activity in the emerging amphibian model, Silurana (Xenopus) tropicalis. Environ. Sci. 2007;14(6):285-96. PMID: 18030284
Daniel B. Pickford, Severine Larroze, Minoru Takase, Naoko Mitsui, Osamu Tooi and Noriaki Santo: Investigating the potential for impacts of environmental endocrine disrupters on wild populations of amphibians in UK and Japan: status of historical databases and review of methods. Environ. Sci. 2007;14(6):297-317. PMID: 18030285
【UK-J Studentship 】
Goodhead RM, Tyler CR: Endocrine disrupting chemicals and their environmental impacts. In: Organic Pollutants. Edited by Walker C; In press.
Tyler CR, Goodhead RM: Impacts of endocrine disruption on wildlife of Britain and Ireland. In: Silent Summer -The Status of Wildlife in Britain and Ireland. Edited by McClean N (Foreword by David Attenborough); In press.
【Related papers】
Iguchi, T., Irie, F., Urushitani, H., Tooi, O., Kawashima, Y., Roberts, M. Norrgren, L. and Hutchinson, T.H. Availability of in vitro vitellogenin assay for screening of estrogenic and anti-estrogenic activities of environmental chemicals. Environ. Sci.,13: 161-183, 2006.
Louis J. Guillette Jr., Thea M. Edwards, and Brandon C. Moore: Alligators, Contaminants and Steroid Hormone. Environ. Sci. 2007;14(6):331-47. PMID: 18030287
Nagae M, Shiroyama K, Inoue M, Hara A, Takao Y, Kohra S, Ishibashi Y, Tominaga N, Yoshihara S, Arizono K: Estrogenic potency of a bisphenol A metabolite on vitellogenin synthesis in medaka, Oryzias latipes. Journal of Health Science 2005, 51(1):93-95.
Nakada N, Okayasu Y, Yasojima M, Miyajima K, Komori K, Suzuki Y, Tanaka H: Fate of estrogenic compounds and estrogenic activity in wastewater treatment process. In: 2nd Joint Specialty Conference for Sustainable Management of Water Quality Systems for the 21st Century: Working to Project Public Health: 2005; 2005: 298-304.
Nakada N, Takada H, Sato N, Suzuki M, Tanaka H, Nakajima F, Furumai H: Removal of estrogens, endocrine disrupters and other wastewater contaminants by soil aquifer treatment. In: Proceedings of International workshop on rainwater and reclaimed water for urban sustainable water use, Core Research for Evolutional Science and Technology (CREST): 2005; 2005: 127-131.
Nakada N, Yasojima M, Okayasu Y, Komori K, Tanaka H, Suzuki Y: Fate of oestrogenic compounds and identification of oestrogenicity in a wastewater treatment process. In: IWA International Conference on Sustainable Development of Chemical Industries with the Environment Waste and Wastewater Management: 2005; Tsukuba, Japan; 2005: 55-58.
Takada H, Shinohara H, Tanishima T, Managaki S, Kojima S, Nakada N, Tanaka H: Estrogenic compounds, pharmaceuticals, and synthetic-detergent-derived chemicals in secondary effluent and their removal during advanced treatment. In: Proceedings of International workshop on rainwater and reclaimed water for urban sustainable water use, Core Research for Evolutional Science and Technology (CREST): 2005; 2005: 121-126.
Tanaka H: Key factors to sustain the water environment created by reclaimed wastewater. In: Proceedings of International workshop on rainwater and reclaimed water for urban sustainable water use, Core Research for Evolutional Science and Technology (CREST): 2005; 2005: 35-42.
Iguchi T, Watanabe H, Katsu Y: Application of ecotoxicogenomics for studying endocrine disruption in vertebrates and invertebrates. Environmental Health Perspectives 2006, 114:101-105.
Jolly C, Katsiadaki I, Le Belle N, Mayer I, Dufour S: Development of a stickleback kidney cell culture assay for the screening of androgenic and anti-androgenic endocrine disrupters. Aquatic Toxicology 2006, 79(2):158-166.
Katsiadaki I, Morris S, Squires C, Hurst MR, James JD, Scott AP: Use of the three-spined stickleback (Gasterosteus aculeatus) as a sensitive in vivo test for detection of environmental antiandrogens. Environmental Health Perspectives 2006, 114:115-121.
Katsu Y, Kohno S, Oka T, Mitsui N, Tooi O, Santo N, Urushitani H, Fukumoto Y, Kuwabara K, Ashikaga K, Minami S, Kato S, Ohta Y, Guillette LJ, Iguchi T: Molecular cloning of estrogen receptor alpha (ER-alpha; ESR1) of the Japanese giant salamander, Andrias japonicus. Molecular and Cellular Endocrinology 2006, 257-258:84-94.
Mitsui N, Fujii T, Miyahara M, Oka T, Kashiwagi A, Kashiwagi K, Hanada H, Urushitani H, Santo N, Tooi O, Iguchi T: Development of metamorphosis assay using Silurana tropicalis for the detection of thyroid system-disrupting chemicals. Ecotoxicology and Environmental Safety 2006, 64(3):281-287.
Oka T, Mitsui N, Hinago M, Miyahara M, Fujii T, Tooi O, Santo N, Urushitani H, Iguchi T, Hanaoka Y, Mikami H: All ZZ male Xenopus laevis provides a clear sex-reversal test for feminizing endocrine disruptors. Ecotoxicology and Environmental Safety 2006, 63(2):236-243.
Amano H, Fujita T, Hiramatsu N, Shimizu M, Sawaguch S, Iatsubara T, Kagawa H, Nagae M, Sullivan CV, Hara A: Egg yolk proteins in gray mullet (Mugil cephalus): Purification and classification of multiple lipovitellins and other vitellogenin-derived yolk proteins and molecular cloning of the parent vitellogenin genes. Journal of Experimental Zoology Part A-Ecological Genetics and Physiology 2007, 307A(6):324-341.
Andersson C, Katsiadaki I, Lundstedt-Enkel K, Orberg J: Effects of 17alpha-ethynylestradiol on EROD activity, spiggin and vitellogenin in three-spined stickleback (Gasterosteus aculeatus). Aquatic Toxicology 2007, 83(1):33-42.
Björkblom C, Olsson P-E, Katsiadaki I, Wiklund T: Estrogen- and androgen-sensitive bioassays based on primary cell and tissue slice cultures from three-spined stickleback (Gasterosteus aculeatus). Comparative Biochemistry and Physiology C 2007, 146(3):431-442.
Iguchi T, Watanabe H, Katsu Y: Toxicogenomics and ecotoxicogenomics for studying endocrine disruption and basic biology. General and Comparative Endocrinology 2007, 153(1-3):25-29.
Johnson AC, Williams RJ, Simpson P, Kanda R: What difference might sewage treatment performance make to endocrine disruption in rivers? Environmental Pollution 2007, 147(1):194-202.
Katsu Y, Hinago M, Sone K, Urushitani H, Guillette LJ, Iguchi T: In vitro assessment of transcriptional activation of the estrogen and androgen receptors of mosquitofish, Gambusia affinis affinis. Molecular and Cellular Endocrinology 2007, 276(1-2):10-17.
Pettersson M, Hahlbeck E, Katsiadaki L, Asplund L, Bengtsson BE: Survey of estrogenic and androgenic disruption in Swedish coastal waters by the analysis of bile fluid from perch and biomarkers in the three-spined stickleback. Marine Pollution Bulletin 2007, 54(12):1868-1880.
Rushbrook BJ, Katsiadaki I, Barber I: Spiggin levels are reduced in male sticklebacks infected with Schistocephalus solidus. Journal of Fish Biology 2007, 71(1):298-303.
Suzuki Y, Harada A, Nakada N, Kitamura K, Yamashita N, Tanaka H, Sato N, Ito M, Komatsu T, Shinohara H, Murakami M, Takada H, Furumai H: Multiple evaluation of urban water quality in comparison with nationwide distribution of river water qualities. In: Proceedings of 2nd International Workshop on Rainwater and Reclaimed Water for Sustainable Water Use: 2007; 2007: 69-74.
Tanaka H: New challenge of municipal wastewater treatment for supporting sound water cycle. In: Proceedings of the 2007 Environmental Societies Joint Conference, Korea-Japan Special Symposium: 2007; 2007: 60-71.
Aniagu SO, Williams TD, Allen Y, Katsiadaki I, Chipman JK: Global genomic methylation levels in the liver and gonads of the three-spine stickleback (Gasterosteus aculeatus) after exposure to hexabromocyclododecane and 17-beta oestradiol. Environment International 2008, 34(3):310-317.
Björkblom C, Salste L, Katsiadaki I, Wiklund T, Kronberg L: Detection of estrogenic activity in municipal wastewater effluent using primary cell cultures from three-spined stickleback and chemical analysis. Chemosphere 2008, doi:10.1016/j.chemosphere.2008.07.052.
Brown MM, Williams TD, Chipman JK, Katsiadaki I, Sanders M, Craft JA: Construction of subtracted EST and normalised cDNA libraries from liver of chemical-exposed three-spined stickleback (Gasterosteus aculeatus) containing pollutant-responsive genes as a resource for transcriptome analysis. Marine Environmental Research 2008, 66(1):127-130.
Geoghegan F, Katsiadaki I, Williams TD, Chipman JK: A cDNA microarray for the three-spined stickleback, Gasterosteus aculeatus L., and analysis of the interactive effects of oestradiol and dibenzanthracene exposures. Journal of Fish Biology 2008, 72(9):2133-2153.
Johnson AC, Ternes T, Williams RJ, Sumpter JP: Assessing the concentrations of polar organic microcontaminants from point sources in the aquatic environment: Measure or model? Environmental Science & Technology 2008, 42(15):5390-5399.
Katsu Y, Ichikawa R, Ikeuchi T, Kohno S, Guillette LJ, Iguchi T: Molecular cloning and characterization of estrogen, androgen, and progesterone nuclear receptors from a freshwater turtle (Pseudemys nelsoni). Endocrinology 2008, 149(1):161-173.
Katsu Y, Kohno S, Hyodo S, Ijiri S, Adachi S, Hara A, Guillette LJ, Iguchi T: Molecular cloning, characterization and evolutionary analysis of estrogen receptors from phylogenetically ancient fish. Endocrinology 2008, doi:10.1210/en.2008-0670.
Kohno S, Katsu Y, Iguchi T, Guillette LJ, Jr.: Novel approaches for the study of vertebrate steroid hormone receptors. Integrative and Comparative Biology 2008, doi:10.1093/icb/icn080
Naidoo V, Katsu Y, Iguchi T: The influence of non-toxic concentrations of DDT and DDE on the old world vulture estrogen receptor alpha. General and Comparative Endocrinology 2008, doi:10.1016/j.ygcen.2008.08.010.
Oka T, Tooi O, Mitsui N, Miyahara M, Ohnishi Y, Takase M, Kashiwagi A, Shinkai T, Santo N, Iguchi T: Effect of atrazine on metamorphosis and sexual differentiation in Xenopus laevis. Aquatic Toxicology 2008, 87(4):215-226.
Paull GC, Lange A, Henshaw AC, Tyler CR: Ontogeny of sexual development in the roach (Rutilus rutilus) and its interrelationships with growth and age. Journal of Morphology 2008, 269(7):884-895.
Sanchez W, Katsiadaki I, Piccini B, Ditche JM, Porcher JM: Biomarker responses in wild three-spined stickleback (Gasterosteus aculeatus L.) as a useful tool for freshwater biomonitoring: A multiparametric approach. Environment International 2008, 34(4):490-498.
Sanders MB, Sebire M, Sturve J, Christian P, Katsiadaki I, Lyons BP, Sheahan D, Weeks JM, Feist SW: Exposure of sticklebacks (Gasterosteus aculeatus) to cadmium sulfide nanoparticles: Biological effects and the importance of experimental design. Marine Environmental Research 2008, 66(1):161-163.
Tyler CR, Filby AL, van Aerle R, Lange A, Ball S, Santos EM: Fish toxicogenomics. In: Comparative Toxicogenomics. Edited by Hogstrand C, Kille P; In: Advances in Experimental Biology vol. 2. Series editors: Wilson, R, Thorndyke M; Amsterdam, The Netherlands: Elsevier; 2008: 75-132, 324-325.
van Aerle R, Kille P, Lange A, Tyler CR: Evidence for the existence of a functional Kiss1/Kiss1 receptor pathway in fish. Peptides 2008, 29(1):57-64.
Iguchi T, Katsu Y: Commonality and difference in mechanisms of endocrine disruption in various animal species. BioScience In press.
Tyler CR, Jobling S: Fish, sex and gender-bending chemicals – The feminization of fish living in English rivers. BioScience In press.